Running back has become a desperate need for the San Francisco 49ers.

Look no further than how the running game fared against the Packers on Sunday night. While the offensive line didn't do Trey Sermon any favors, it is clear that he isn't clicking yet into the offense. It is why he was a healthy scratch Week 1 with Elijah Mitchell getting the nod over him.

Speaking of Mitchell, who knows where he is at with his shoulder injury? Regardless, it is a bit concerning that he has already sustained an injury after two games of being the workhorse. He may not be built for it quite yet. The 49ers offense has a problem on their hands if they cannot effectively and consistently run the football. There is one player who could be of intrigue for the 49ers and that is Colts running back Marlon Mack.

Mack and the Colts have agreed to seek a trade, according to Tom Pelissero of NFL Network. The issue with Mack is that he is coming off an Achilles tear, so that could be a red flag to the 49ers. But it is not like they have let significant injuries deter them from players before. And with running back in a state of emergency, this is a player who could potentially settle the running game. The 49ers have made a deal with the Colts before, so it wouldn't be surprising to see a call made.