After last year’s title race went down to the final day of action, here are the best bets for Matchday 1 of the 2022-23 Premier League season.

As Europe’s topflight returns after a summer of international action, new faces like Darwin Nunez and Erling Haaland headline the first week of Premier League play. Reigning champs Manchester City already start their season with a tough matchup, taking on a top-seven opponent in West Ham United.

Here are our best bets for Matchday 1’s Premier League slate (odds via DraftKings Sportsbook and PointsBet; pick confidence based on a 1-to-5-star scale).


Matchday 1’s Premier League Schedule and Odds

(odds via DraftKings Sportsbook)

Crystal Palace (+350) vs. Arsenal (-120)

Fulham (+950) vs. Liverpool (-340)

Leeds (+130) vs. Wolves (+220)

Newcastle (-150) vs. Nottingham Forest (+475)

Tottenham (-275) vs. Southampton (+750)

Bournemouth (+275) vs. Aston Villa (+105)

Everton (+425) vs. Chelsea (-155)

Leicester (+100) vs. Brentford (+260)

Manchester United (-170) vs. Brighton (+500)

West Ham (+750) vs. Manchester City (-285)