Jurgen Klopp fears this season will be the toughest of his career as Liverpool navigate the unique challenges of defending the Premier League title in the coronavirus age.

Klopp's side have already seen Sadio Mane and Thiago Alcantara briefly sidelined by Covid-19 this season, while a host of injuries have also taken their toll.

The delayed start to this season, a result of the previous campaign's three-month hiatus because of the pandemic, means teams are being stretched to breaking point by the gruelling schedule.

Liverpool boss Klopp has lost Virgil van Dijk to a knee injury that will sideline him for most of the season, with Joel Matip, Naby Keita and Thiago missing the midweek Champions League win over Ajax because of knocks.