Amid all the offseason questions about their pitching, the Red Sox took comfort in knowing they had Jon Lester, Josh Beckett and Clay Buchholz heading their starting rotation. But the Big Three continue to come up small. Last night, it was Lester's turn. Seeking to avoid a third straight losing series, the Red Sox turned to Lester, who needed 108 pitches to get through five innings. Surely, the ace left-hander wasn't helped by center fielder Marlon Byrd's two-out error, which extended a three-run first inning, but he wasn't economical in his other four innings either.