Christian Pulisic is expected to be out for up to two months with a knee injury, Chelsea head coach Graham Potter confirmed on Wednesday.
The United States international limped out of last week's Premier League home defeat to Manchester City and has since undergone a series of tests to determine the extent of the problem.
Speaking ahead of Thursday's trip to Fulham, Potter told a news conference: "Christian is a couple of months we think, hopefully less, but that's the timeframe there."
The news will come as a significant blow to Pulisic, as sources had told ESPN the 24-year-old was eyeing a move away from Stamford Bridge this month.