Vidal Nuno will make his first major league start for the Yankees in the second game of a doubleheader today in Cleveland.

Infielder Corban Joseph will be the Yankees’ 26th man since MLB rules allow an extra player for days when two games are played. Joseph was promoted from Triple-A Scranton/Wilkes-Barre on April 30 and sent back May 1 and didn’t appear in a game. He is exempt from the rule that requires optioned players to stay in the minors for 10 days because he will be returned to Triple A after today’s second game.

And right-hander Brett Marshall could get his first taste of the major leagues.

After yesterday’s 4-2 win over the Royals at Kauffman Stadium the Yankees announced Nuno would start the second game today.

Nuno, a 25-year-old lefty who is from tiny Baker University in Kansas and an alumni of the independent Frontier League, has worked one big league game. On April 29 he tossed three scoreless innings against the Astros in a 9-1 loss to Houston.

He was 2-0 with a 1.54 ERA in four starts for Scranton.

Marshall will be on hand in Cleveland and could be needed in relief because Joe Girardi has used David Robertson and Mariano Rivera in four of the past five games and the last two.

“I don’t know if either one is an option,’’ Girardi said of his setup man and closer. “I will figure it out [today].’’

Preston Claiborne is a candidate to be sent out for Marshall, who was supposed to start for Scranton yesterday, but didn’t. The 23-year-old was 2-2 with a 4.60 ERA in six games at Triple-A.