Sam Bradford was ruled out Friday for Sunday’s game against Cleveland at Twickenham Stadium and Vikings coach Mike Zimmer said Case Keenum again will start at quarterback.

Bradford will sit out for the sixth time in seven games with a knee injury. He has been replaced on all the previous occasions by Keenum, who has a 3-2 record as a starter.

The Vikings practiced at The Hazelwood Centre, the training ground for the London Irish rugby team. Aside from Bradford, also not practicing and listed as out for Sunday were guard Jeremiah Sirles (knee) and defensive end Stephen Weatherly (knee).

The Vikings listed as questionable wide receivers Stefon Diggs (groin, ankle) and Michael Floyd (hamstring), tackle Riley Reiff (knee), guard Nick Easton (calf) and cornerback Mackensie Alexander (hip). Diggs, Reiff and Alexander were full participants in practice while Floyd and Easton were limited.