After another head-scratching loss on Tuesday, Syracuse coach Jim Boeheim told reporters, "If you play well, seeding doesn't matter."

The Orange have lost four of five — the latest a 67-62 home setback vs. ACC basement club Georgia Tech. Boeheim's logic makes perfect sense, but we all know there's a drastic difference between facing a No. 16 seed and a No. 15 seed in the field of 68. (i.e. Florida Gulf Coast vs. Georgetown last year).

As of today, Syracuse is officially a No. 2 seed in our bracketology projections. And that's likely where the Orange will remain heading into Selection Sunday.

Of course, success in the NCAA tournament hinges heavily upon matchups. It's completely hypothetical and perhaps far-fetched to suggest projected No. 15 seeds Mercer, Georgia State, Davidson or Boston University are capable of pulling off the upset of all upsets.

But it's far more important to point out just how vulnerable Syracuse is to support the bold headline on this article. Consider the fact that we were brainwashed for much of January and early February when the Orange were undefeated but not, by any stretch, dominating opponents. It's why Boeheim said in Syracuse's win against Maryland that the team's struggles aren't necessarily a flipped script.

In Syracuse's defense, the loss of Jerami Grant drastically hurts the team's offensive capabilities because it puts unnecessary pressure on All-Americans C.J. Fair and Tyler Ennis. At the same time, it also shows how bare the offensive cupboard is without Grant. If sharpshooter Trevor Cooney is misfiring, as he has the past few games, then outside of Fair and Ennis, we're looking at defensively reliable big men who are just as unreliable on offense.

Syracuse's 2-3 matchup zone can cause headaches for most teams, but as bottom-feeder ACC teams have proven, slowing the game down only exposes the weaknesses that had been there all along.

Seeding might not have a thing to do with how well a team's playing, true. But as No. 13 seed Vermont proved vs. No. 4 seed Syracuse in 2005, the wrong matchup can spell an early exit.

TIP-OFF: The bifurcated nature of the American Athletic Conference has resulted in No. 9 Louisville not facing many critical end-game situations this season. But when the Cardinals have, they've sometimes failed to execute as they did over the weekend against Memphis. The defending national champs face another squad from the league's upper tier tonight at No.18 Southern Methodist (7 p.m. ET, CBS Sports Network).

The Mustangs have endured a few hiccups in league play themselves but enter tonight's contest on a three-game run that includes a road triumph at UConn. Nic Moore (14.1 ppg, 4.7 apg) is SMU's offensive catalyst who will also likely have to deal with Louisville's Russ Smith on the defensive end.