In 2010, the USC Trojans were hit with unprecedented sanctions by the NCAA.

Included in the sanctions were a two-year bowl ban and 30 scholarship reductions across a three-year period.

The NCAA began investigating USC in 2006, ultimately determining running back Reggie Bush and his family received money and other perks from sports marketers while he played for the Trojans during 2004 and 2005.

From the Los Angeles Times:

USC fought the NCAA over allegations against Bush because school officials, including football coach Pete Carroll, said there was no way they could have known the running back and his family were benefiting from free rent and other perks in suburban San Diego, so far from the university's downtown Los Angeles campus. But the NCAA was convinced that USC — specifically running backs coach Todd McNair — knew or should have known about the rules violations.

USC was tagged with the "lack of institutional control" label and then hammered by the NCAA.