"Texans receiver Andre Johnson will not play at Cincinnati because of the strained hamstring in his left leg.
Johnson, who was injured after catching four passes for 97 yards in Sunday's 17-10 victory over Atlanta, will miss his seventh game because of hamstring injuries.
"It's very disappointing," Johnson said after Friday's practice. "You work your butt off to get back after missing six games, and then to have something like this to happen again is very frustrating.
"At the same time, the team's in a great position, and I'm just trying to do everything I can to get back. I'm rehabbing. I ran a little bit today on the treadmill."
Jacoby Jones will start his seventh game in place of Johnson.
"It's a day-by-day thing," Johnson said. "It's not as bad as it was the previous injury (torn right hamstring) I had.""