Dwight Powell had 15 points and seven rebounds and No. 10 seed Stanford wrapped up its second straight upset at the free throw line, knocking off No. 2 Kansas 60-57 in the South Regional on Sunday.

Chasson Randle added 13 points, six steals and four assists for the Cardinal (23-12), who advanced to the round of 16 for the first time since 2008 - also their last NCAA appearance. They beat No. 7 seed New Mexico on Friday.

Freshman Andrew Wiggins had just four points on 1-for-6 shooting with four turnovers in his final college game for Kansas (25-10). Wiggins is a likely NBA lottery pick and had averaged 28 points the previous four games.

Kansas is the second No. 2 seed to be eliminated. Villanova lost 77-65 to seventh-seeded Connecticut in the East Regional.

Tarik Black had 18 points and six rebounds for the Jayhawks, but he fouled out with 5:25 to go. Conner Frankamp had 12 points on four 3-pointers, the last two in the final 23 seconds to make it close after Stanford had pulled ahead by seven.

Stanford was 9 for 12 at the free throw line over the final 2:04 and needed all those points. Frankamp's second 3-pointer narrowed the gap to 59-57 with 14.9 seconds left.

Anthony Brown hit just one of two free throws with 12.9 seconds and Frankamp banged a third 3-point attempt off the glass near the buzzer in a bid to tie it.

Kansas went to a full-court press down five points with about 11 minutes to play and forced five turnovers the next 6 minutes to tie it

Kansas had been 0 for 10 from 3-point range for the tournament, seven of the misses against Eastern Kentucky, before Frankamp connected with 3:34 to go in the half.