The Panthers were hoping the return of center Ryan Kalil would spark their running game.

It didn’t work early, and now they’re without the five-time Pro Bowler again, and faced with more immediate problems.

Kalil has aggravated the neck injury that kept him out the previous five games, and is questionable to return. He has been replaced by Tyler Larsen, who took over when Kalil came up with the problem before their Week Two game.