Terry Francona said that for the first few innings tonight, it looked the Red Sox were still enjoying their day off.

Seattle took a 2-0 lead in the first inning and led 4-2 after four innings.

But despite a lineup that had to be changed when Kevin Youkilis and Marco Scutaro were scratched with stiff backs, the Sox scored the final four runs and came away with a 6-4 victory.

Mike Aviles, who replaced Scutaro, had a sacrifice fly in the second inning. Jed Lowrie, subbing for Youkilis, homered in the fifth.

"Just because you're coming off the bench doesn't mean you're not a winning player," Lowrie said. "The expectations are still there. We all know that."

Josh Reddick had the big hit, a two-run blast to right field in the sixth inning off Blake Beavan.