The Yankees broke the bank on free agents in the offseason, but it was one of their newest acquisitions who delivered among the most significant hits of the year on Friday night.

Martin Prado, brought over from the Diamondbacks right before the trade deadline, smacked a game-winning single with two outs and the bases loaded in the bottom of the ninth to give the Yankees a 4-3 win over the White Sox in The Bronx.

“I can describe that as one of the biggest moments of my career,” said Prado, who also hit a two-run homer in the third inning. “Not personal-wise. Just getting a win for the Yankees means a lot for anyone.”

Especially for the Yankees, who won their second straight with their season on life support.

“This was the biggest win of the year, for sure,” Brett Gardner said. “At this point, we’ve got to win every game we have a chance to win. I thought this was a game we had to win.”

A victory seemed unlikely when the Yankees fell behind 3-0 just three batters into the game, after Shane Greene surrendered a three-run homer to rookie phenom Jose Abreu.