Opening Day is finally here, and the Phillies' quest for a sixth straight division title begins with a three-game set in Pittsburgh.

While six weeks of spring was enough to answer the burning question of who will be the utility infielder and the final arm in the bullpen, there are a number of far more pressing concerns still looming as the Phillies begin the 2012 season.

• 1. When will Ryan Howard and Chase Utley return?

Obviously no question looms larger for the Phillies, who open the season for the second straight season without their starting second baseman, only now they'll be missing their cleanup hitter, too.