Eli Manning isn’t the slightest bit scared about practicing or playing on his surgically repaired ankle. Having to get used to an entirely new offensive system and coordinator? That has the two-time Super Bowl MVP sweating a bit.

“Yeah, it is different. You come into the season a little nervous; you just don’t have [the same comfort],’’ Manning said Monday as the Giants opened training camp. “You have a good feel for it, but not to where I want it to be. That’s with repetition and more plays.

“It’s a different feeling this time of year than in previous years. We’ve still got a lot of work to do and a lot to improve on to get comfortable, myself with my teammates and everything that goes on with being successful in an offense. I know we’ve got a lot of work to do. But we’re excited about that challenge.’’

Manning insists he won’t be challenged physically, saying he’s fully recovered from his April ankle surgery. And even though he didn’t run with his Giants teammates Monday, Tom Coughlin said, “He didn’t run last year, either.’’ Manning did throw on another field with coaches, and after practicing fully in last month’s mini-camp isn’t expected to be limited at all.

“The ankle feels great, 100 percent. Don’t feel it, don’t think about it. It’s not an issue,’’ Manning said. “I’m excited; excited to be in another training camp, get the season kicked off and get back to work. It’s an exciting time. This is what you look forward to.”

Manning will be doing a lot of adjusting, although none of it surprising.