Faced with a 2-1 hole, an uncertain rotation, a flu bug making the rounds and a scoring tandem in the tank, coach Mike Woodson sounded desperate at yesterday’s practice.

It’s crisis time for the Knicks going into Game 4 of this second-round series tomorrow at Bankers Life Fieldhouse, where they are 0-3 this season.

“We’re going to need everyone playing [tomorrow] on all high cylinders,’’ Woodson warned. “We don’t want to go home down 3-1. That would be a tough climb for us. Tuesday’s game is very, very important.’’

The Knicks are in a dire predicament. Their offense can’t play sicklier than it did in the “Saturday Night Fever” 82-71 loss in Indianapolis.

“We play better when our backs are against the wall,’’ Amar’e Stoudemire said.

You could not hang all the blame on Carmelo Anthony, who scored a modest 21 points, missed his final six shots and committed four turnovers. Everyone struggled, right down to their trio of point guards, Raymond Felton, Jason Kidd and Pablo Prigioni.

Woodson acknowledged he has to figure out a fluctuating rotation that just added a rusty Stoudemire at the most sensitive time.

“At this stage of the game, your team, most playoff teams, are pretty set,’’ Woodson said. “And we’re kind of jumping around a little bit. We’ll figure it out.’’

Or they won’t and a once-promising season will never see Miami in May.

In Game 3, the Knicks didn’t resemble the dynamo club that went 54-28 during the regular season. They made a season-low three 3-pointers and were crushed again on the boards, allowing the Pacers 18 offensive rebounds. They have turned Indiana’s 7-foot-2 center Roy Hibbert into Kareem Abdul-Jabbar.

Anthony petered out in the fourth quarter after being roughed up by Pacers power forward David West. Anthony, who took just three shots in the fourth, doesn’t seem as relaxed and confident with his wingman J.R. Smith on the fritz and ridden with a viral infection.