"Running back Darren McFadden was ruled out of Sunday's game against the Denver Broncos with a sprained right foot.
McFadden, who led the NFL in rushing before the injury, has fallen to eighth with 614 yards.'
McFadden had only two carries before leaving in the first quarter of the Raiders' 28-0 loss to Kansas City on Oct. 23.
Michael Bush (237 yards on 60 carries this season) will get his first start this season.
With the Raiders having a game next Thursday night in San Diego, coach Hue Jackson wasn't sure if McFadden would miss more than the Sunday's game but said McFadden is "making progress."
"To me, that mid-foot sprain, you just got to take it day-to-day," Jackson said. "I don't want to say, 'Boy, it's going to be this or that.' I think every day he's gotten better, a lot better, and I just think we'll continue to evaluate that. I'm not going to put him out there if he's not healthy.""