It wasn't pretty at any point for Louisville over the first weekend of the NCAA tournament, but the fourth-seeded Cardinals are back in familiar territory.

Louisville advanced to its third consecutive Sweet 16 with a rough-and-tumble 66-51 win over Saint Louis on Saturday at the Amway Center here in Orlando.

Luke Hancock led all scorers with 21 points and Louisville (31-5) stifled Saint Louis, holding the Billikens to 0-of-15 3-point shooting.

The win was U of L coach Rick Pitino's 50th tournament victory in his career. Louisville will play the winner of Wichita State and Kentucky's game in St. Louis, which tips off at 2:45 p.m. Sunday