The Buffalo Bills have a crisis at quarterback two weeks before the start of the regular season.

They are down to one healthy quarterback — undrafted rookie Jeff Tuel — in the wake of Saturday’s 30-7 loss to the Washington Redskins.

Veteran Kevin Kolb was knocked out of Saturday’s game against the Washington Redskins with concussion-like symptoms after taking a blow to the head. Rookie EJ Manuel is out this week — at the least — after undergoing minor knee surgery last week.

The prospect of Tuel starting the season opener against New England on Sept. 8 looms as a distinct possibility.

“That’s kind of scary to look at with only one guy back there” defensive tackle Kyle Williams said. “Hopefully it’s not too serious with Kevin. Hopefully EJ can continue to get better. Jeff’s done a good job when he’s played. But you don’t want just one going into any game.”

General Manager Doug Whaley said in the locker room after the game the Bills were hoping to have a quarterback signed and on hand for the next practice at 8 a.m. Monday in Orchard Park.

“Absolutely” Whaley said. “All we have is one arm so we’ve got to get somebody in. There’s not a lot of options. We’ve got guys beating the pavement right now.”

According to multiple media reports late Saturday the Bills had scheduled tryouts today with Matt Leinart and John Beck. Leinart has an 8-10 career record over parts of six NFL seasons. Beck played for Miami in 2007 and Washington in 2009 and is 0-7 as a starter.

The Bills could shift receiver Brad Smith to quarterback as well as an emergency replacement and coach Doug Marrone threw running back Fred Jackson’s name out as well.

“We had a plan going into the season” coach Doug Marrone said. “Obviously Brad is part of those plans as well as Fred Jackson.”

The Bills’ exhibition finale is in five days against Detroit at Ralph Wilson Stadium.

Marrone would not rule out the possibility of Manuel returning in time to face the Patriots although that would require a dramatic recovery even though the Bills have described his surgery as minor.

“That’s what I’m hoping for” Marrone said. “He had a procedure done. He was with us on the field the other day — just watching and observing. I think you just have to wait for that period where the doctor looks at him and says here’s where we are. People recover so differently from minor stuff.”

Regardless of when Manuel comes back Kolb’s injury looms as a major concern.

The seventh-year veteran took a blow to the head at the end of an 8-yard scramble around right end midway through the first quarter. Kolb dived head-first to the ground with Redskins linebacker Brandon Jenkins in pursuit. Jenkins’ knee caught the back of Kolb’s helmet as Jenkins tumbled to the ground.