On the sixth snap of the Jets’ 2017 season, with the sun shining in Buffalo, Bills running back LeSean McCoy collected a screen pass from Tyrod Taylor near the right hashmarks. He cut to the inside at the line of scrimmage, sending linebacker Darron Lee to the turf, then swerved left as defensive lineman Muhammad Wilkerson fell backward, sprawling in surprise.

McCoy reversed fields, sprinting from one sideline the the other. By the time he reached the first-down marker, McCoy had gained 21 yards. Multiple Jets lay on the ground in his wake. The catch and run set the tone for a huge day from McCoy, who finished with 169 yards from scrimmage in the Bills’ 21-12 win. He accounted for five plays of 18 or more yards, including three runs.

It’s this type of performance the Jets are hoping to avoid when they face the Bills for the second time this season Thursday night at MetLife Stadium. And while Todd Bowles’ defensive players respect McCoy’s athleticism and explosiveness, they believe their development as a run defense will shine through in prime time this week.

“He’s not a superhero,” defensive lineman Steve McLendon told the Daily News Tuesday of McCoy. “You don’t want to make it seem like he can’t be stopped.