Cleveland Indians designated hitter Edwin Encarnacion left Friday's American League Division Series game against the New York Yankees in the bottom of the first inning with an apparent right ankle sprain that appeared to be significant.

His ankle bent at a grotesque angle as he tried to return to second base on a soft line-drive out by teammate Jay Bruce.

Encarnacion had reached base after being hit in the knee by a pitch from Yankees starter CC Sabathia, and he advanced to second base on a Carlos Santana single. He was doubled off second by Yankees shortstop Didi Gregorius on the Bruce lineout.

Encarnacion writhed in pain in the infield dirt before being helped off the field by Cleveland's training staff. He was unable to put any weight on his right leg on his way to the dugout.