Once, long ago, David did beat Goliath. The Washington Generals have actually beaten the Harlem Globetrotters.

Once.

"Anything can happen," Cavaliers coach Byron Scott said Tuesday. "Just like boxers. James Buster Douglas against Mike Tyson. Nobody in the world thought it would happen."

It did then, so it could, now. The 22-45 Cavaliers have a chance against the 52-14 Miami Heat, and their 23-game winning streak.

That's true even after learning Tuesday that they will be without rookie guard Dion Waiters. An MRI on Waiters' sore left knee revealed a loose fragment of cartilage, which will force him to miss at least a week. Arthroscopic surgery remains a real possibility when Waiters is re-evaluated after a week of rest.

Without Waiters, Wayne Ellington will start, and the backup point guard job -- once filled by Waiters while Kyrie Irving is out with a sprained left shoulder -- now will be split between Ellington and Daniel Gibson.

Scott said he hopes to sign a player soon to add an extra body for practice, but that won't help against Miami on Wednesday. In 23 consecutive victories, the Heat is averaging 105.4 points on 51 percent shooting. Opponents are at 94.2 points and 44.9 percent. On average, their victories have been decisive and dominant.

"I'm sure from their standpoint, they're on a high," Scott said. "When you're playing that well, obviously you have to have some luck in there during that streak, some things have to go well. But you also almost get to the point where you feel you're invincible. That you can't lose. I think that's where they are right now."