Just call him Frazzled Fred.

Fred Wilpon was “irate” after learning of Giancarlo Stanton’s recent trade to the Yankees, according to an industry source, continuing a pattern of hand-wringing by the Mets co-owner following a splash by his crosstown rival.

“Fred is pissed every time the Yankees make a move,” said a person who speaks to Wilpon regarding baseball matters. “And he always seems surprised.”

At issue is the Yankees’ willingness to take on huge contracts, in the process embarrassing the Mets for their restrained spending habits. The Yankees, who acquired Stanton from the Marlins earlier this month for Starlin Castro and two prospects, will pay the All-Star slugger $265 million over the life of his remaining contract if he doesn’t opt out. Jacoby Ellsbury and Masahiro Tanaka are other current Yankees in the middle of contracts worth more than $100 million.

Wilpon believes such an economic model is “unsustainable,” according to a source, a sentiment he has held for several years as the Yankees have made blockbuster acquisitions.

Wilpon’s reaction to the Stanton deal was hardly unexpected by those around the team patriarch — he was so rankled when the Yankees traded for Alex Rodriguez in 2004, according to sources, that he called a Mets executive who was on a family vacation to complain.

“[Wilpon] keeps saying the Yankees can’t keep this model up,” a source said. “And they keep showing that they can.”

Wilpon declined comment through a team media relations official.

Another source added that Wilpon, despite stating otherwise a few years ago when he still spoke to the media, is extremely sensitive to how the Yankees conduct business.

“He cares a lot about the Yankees,” the source said.