Even when the Knicks attempt to rest players to prepare for the playoffs, they can’t avoid the injury bug that has plagued them all season.

Who expected Game 82 to be any different?

Pablo Prigioni didn’t finish Wednesday’s regular season finale after suffering a sprained right ankle — X-rays were negative — late in the first quarter of the Knicks’ 98-92 win over Atlanta at the Garden. Iman Shumpert also left the game in the fourth quarter with cramps in his right leg, and Chris Copeland completed a 33-point effort despite his left shoulder “popping out” early in the final period.

“Tough game tonight,” Mike Woodson said. “Iman was mainly cramps. Cope’s fine. He had a hell of a game. He’ll sleep good tonight on that. Pablo will be day-to-day.”

With newly crowned NBA scoring champion Carmelo Anthony, J.R. Smith and Jason Kidd taking the night off, Woodson initially said the Knicks (54-28) had eight available players. But he stuck with just six — leaving starting point guard Raymond Felton in his warmup suit on the bench — once Prigioni headed to the locker room after rolling his ankle on a drive to the basket with 55 seconds left in the first quarter. The 35-year-old rookie guard has started the past 18 games, but Woodson said Prigioni is questionable for Saturday’s 3 p.m. playoff opener against Boston at the Garden.

Copeland expects to play after netting a career-high with his 33 points, becoming the first Knick rookie since Bill Cartwright (1980) with consecutive 30-point games. The forward received treatment on his shoulder after taking a whack early in the fourth before returning.

“I’m good. I’ll be all right,” Copeland said. “It doesn’t feel too good right now . . . but I’m sure it will be fine by Saturday.”