Three catches for Seyi Ajirotutu for the season. One very big one.

Subbing for injured teammate Eddie Royal, Ajirotutu caught a 26-yard touchdown pass from Philip Rivers with 24 seconds left in the game as the Chargers upset the Chiefs 41-38 in Kansas City.

In a wild game with eight lead changes – the most in the NFL since 2011 – Rivers took only 58 seconds to drive the Chargers 78 yards to the winning touchdown.

Rivers completed 70 percent of his passes and threw for 392 yards and three touchdowns in beating the Chiefs for the 11th time in his career against only four losses. The Chargers, who snapped a three-game losing streak, were the heavy underdog, with a 4-6 record to compare to the Chiefs' 9-1. Kansas City hadn't lost a game at home this season.

Rivers was sacked only once and the Chargers didn't have a turnover, while the Chiefs had two.

Ajirotutu, a fourth-year receiver with 19 career receptions entering the game, came in late because of the exit of Royal, who has been suffering from turf toe. His two previous catches for the season came a week ago against Miami while also subbing.

Dwayne Bowe made a one-handed, 7-yard touchdown catch with 1:22 left in the game to give the Chiefs a four-point lead.

In the sixth lead change of the game, Chargers tight end Ladarius Green made a 60-yard run and catch for a touchdown to give the Chargers a 34-31 lead. Green went untouched in single coverage up the middle to score his first touchdown of the season on his longest play of the year.

On the Chiefs previous drive, Ryan Succop kicked a 25-yard field goal with 9:32 left in the fourth quarter to add to the Chiefs' lead, 31-27.

The Chargers had cut the Chiefs' lead to 28-27 early in the fourth, but squandered a chance for a touchdown after reaching the Kansas City 3-yard line.

Eddie Royal got the Chargers to the 4 on a 6-yard catch and Danny Woodhead made a 1-yard catch, but the Chargers then tried a pass and were called for holding, and ended up having to settle for a 30-yard field goal by Nick Novak.

In a wild third quarter with four lead changes, the Chiefs retook the lead when Alex Smith hit tight end Anthony Fasano with a 4-yard touchdown pass to take a 28-24 advantage.

Three minutes earlier, the Chargers converted an interception of Smith into a touchdown, scoring on a 3-yard run by Woodhead.

On a third-down pass, Smith threw high to receiver Donnie Avery, Shareece Wright tipped it and Marcus Gilchrist came down with his third pick of the year. Gilchrist returned the ball to the Kansas City 16. Chargers quarterback Philip Rivers followed with a 13-yard throw to tight end Ladarius Green, and that set up the scoring play for Woodhead, who caught a TD pass at the end of the first half.