This is what most baseball fans have been waiting for, Major League Baseball to send a message that, quite simply, enough is enough.

Enough with the cheating. Enough with ballplayers finding ways to beat the drug-testing system. Enough with their never-ending search for a chemical advantage.

Indeed, what really gets your attention here isn’t so much that MLB is seeking player suspensions relating to the Biogenesis Clinic, but that Bud Selig is going for the throat on this one, looking to suspend Alex Rodriguez and Ryan Braun 100 games each.

You think that won’t get the attention of players everywhere?

First things first: The Yankees probably will be happy if this means A-Rod is done for the season — although it remains to be seen if a suspension affects the insurance money the ballclub could receive if he simply couldn’t play because of his hip surgery.

But they are surely happier because, according to a Yankee source, there has been no indication from MLB that Robinson Cano is in danger of being suspended.

Weeks ago the name of the spokeswoman for Cano’s foundation reportedly turned up on the Biogenesis lists, and even though the Yankee second baseman said it had nothing to do with him, apparently there is no reason to believe that Anthony Bosch, the director of the clinic, has told MLB otherwise.

In any case, Bosch is the crux of the matter now. Apparently he has agreed to testify that he did supply players with PEDs, as was first alleged in the story by the Miami New Times in February.

At this point, neither the Yankees nor their fans care much if A-Rod ever plays again. The Yankees just wish a suspension would improve their chances of voiding the remaining five years and $114 million on his contract, but an MLB person said weeks ago that wouldn’t be the case.

For the moment, the story is MLB making it clear just how hard it is going after a couple of the game’s superstars.

But maybe MLB won’t be able to make 100 games stick. Technically, it would be a first offense for each of them, which would mean a 50-game suspension, but MLB apparently believes it has cause to add a second offense, based on A-Rod and Braun potentially lying to investigators about their involvement with steroids.

It sounds reasonable enough, but you know the Players’ Association will file a grievance, and each case could well end up being decided by an arbitrator.

Still, it’s exactly the right message to send to everyone - players, ballclubs and the fans - after it has become clear that 50-game suspensions weren’t enough of a deterrent for determined cheaters.

Melky Cabrera, for example, cashed in for $16 million last winter from the Blue Jays after being suspended for a positive drug test, ultimately benefiting from the testosterone-aided numbers he put up with the Giants in 2012.

So the time is right for something bigger, something that feels like the chasers have finally caught up to the cheats, after all the years of watching Barry Bonds and Roger Clemens and others mostly avoid punishment for lying about using steroids.