"Before Saturday night, when ESPN released a report claiming Ryan Braun tested positive for a performance-enhancing drug in October, no Milwaukee Brewers player had been accused publicly of such a transgression.

Though it might be a new experience for Brewers fans with regard to one of their own, Braun isn't the first star to face scrutiny for running afoul of Major League Baseball's Joint Drug Prevention and Treatment Program, which was rolled out after the 2003 season.

The two highest-profile players suspended for PEDs under the program have been Rafael Palmeiro and Manny Ramirez, who tested positive not once but twice, in 2009 and again this year.

And while both denied knowingly taking a banned substance - as Braun and his camp already have vehemently done - Palmeiro and Ramirez nevertheless were suspended, their reputations as two of the game's best hitters forever sullied.

Palmeiro's case was especially interesting."